Thymocyte and T cell trafficking relies on signals initiated by G-protein coupled receptors. however the lack of both G-proteins commencing in the DP stage caused a severe T cell phenotype. These mice lacked a thymic medullary region, exhibited thymocyte retention, experienced a peripheral T cell deficiency, and lacked T cell chemoattractant reactions. Yet a noteworthy … Continue reading Thymocyte and T cell trafficking relies on signals initiated by G-protein coupled receptors